Anesthesia Management via an Automated Control System for Propofol, Remifentanil, and Rocuronium Compared to Management by Anesthesiologists: An Investigator-Initiated Study.

Osamu Nagata Yuka MatsukiShuko MatsudaKeita HazamaSaiko FukunagaHideki NakatsukaFumiyo YasumaYasuhiro MaeharaShoko FujiokaKarin TajimaIchiro KondoItaru GinozaMisuzu HayashiManabu KakinohanaKenji Shigemi

Published in: Journal of clinical medicine (2023)

Our three-agent automated control system, which features an improved muscle relaxation monitor and safety mechanism added to the basic control algorithms, maintained sedation, analgesia, and muscle relaxation appropriately in a manner non-inferior to anesthesiologists without compromising safety.

Keyphrases

machine learning
skeletal muscle
single molecule
intensive care unit
mechanical ventilation
postoperative pain