Association between preoperative neurocognitive status and IDH1 mutation status in high-grade gliomas.
Evangelia LioutaAristotelis V KalyvasSpyridon KomaitisEvangelos DrososChristos KoutsarnakisJuan M García-GómezJavier Juan-AlbarracínVasileios K KatsarosTheodosis KalamatianosTheodoros ArgyrakosGeorge StranjalisPublished in: Neuro-oncology practice (2022)
Our findings indicate that IDH1 wild-type HGG patients present greater NCF impairment, in executive functions particularly, compared to IDH1 mutant ones, suggesting that tumor growth kinetics may play a more profound role than other tumor and demographic parameters in clinical NCF of HGG patients.