The Effects of Human Milk Oligosaccharides on Gut Microbiota, Metabolite Profiles and Host Mucosal Response in Patients with Irritable Bowel Syndrome.

Cristina IribarrenMaria K MagnussonLouise K VigsnæsImran AzizIngvild Dybdrodt AmundsenTanja Šuligoj Nathalie Juge Piyush PatelMaria SapnaraLea JohnsenNikolaj SørensenJohanna SundinHans TörnblomMagnus SimrénLena Öhman

Published in: Nutrients (2021)

Supplementation with 2'FL/LNnT modulated the gut microbiota, fecal and plasma metabolite profiles, but not the host mucosal response in IBS. Furthermore, the bifidogenic effect was associated with metabolite modulation. Overall, these findings support the assertion that 2'FL/LNnT supplementation modulate the intestinal microenvironment of patients with IBS, potentially related to health.

Keyphrases

irritable bowel syndrome
human milk
low birth weight
public health
healthcare
stem cells
ulcerative colitis
mental health
social media