Associations of HLA genotypes with antithyroid drug-induced agranulocytosis: A systematic review and meta-analysis of pharmacogenomics studies.

Published in: British journal of clinical pharmacology (2019)

HLA-B*27:05, HLA-B*38:02 and HLA-DRB1*08:03 alleles were associated with ATD-induced agranulocytosis, especially in carbimazole/methimazole-induced agranulocytosis.

Keyphrases

drug induced
liver injury
high glucose
diabetic rats
adverse drug
endothelial cells
emergency department
clinical decision support
electronic health record