Proteomic analysis of extracellular vesicles secreted by primary human epithelial endometrial cells reveals key proteins related to embryo implantation.

Marina Segura-BenítezMaría Cristina Carbajo-GarcíaAna CorachánAmparo FausAntonio PellicerHortensia Ferrero

Published in: Reproductive biology and endocrinology : RB&E (2022)

EV protein cargos are implicated in biological processes related to endometrial receptivity, embryo implantation, and early embryo development, supporting the concept of a communication system between the embryo and the maternal endometrium via EVs. Identified proteins may define new biomarkers of endometrial receptivity and implantation success.

Keyphrases

pregnancy outcomes
endometrial cancer
induced apoptosis
endothelial cells
pregnant women
cell cycle arrest
oxidative stress
birth weight
physical activity
small molecule
endoplasmic reticulum stress
body mass index
cell death
preterm birth
weight gain