The role of vagal innervation on the early development of postoperative ileus in mice.
Martina BrandlhuberPetra BenhaqiBernhard BrandlhuberVanessa KoliogiannisMichael S KasparekMario H MuellerMartin E KreisPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2021)
Afferent nerve signaling to the central nervous system during the development of early POI seems to be mediated mainly via the vagus nerve and to a lesser degree via systemic circulation. During the early hours of POI, the intestinal immune response may be attenuated by vagal modulation, suggesting interactions between the central nervous system and the intestine.