Comparative assessment of genes driving cancer and somatic evolution in non-cancer tissues: an update of the Network of Cancer Genes (NCG) resource.
Lisa DresslerMichele BortolomeazziMohamed Reda KeddarHrvoje MiseticGiulia SartiniAmelia Acha-SagredoLucia MontorsiNeshika WijewardhaneDimitra RepanaJoel NulsenJacki GoldmanMarc PollittPatrick DavisAmy StrangeKaren AmbroseFrancesca D CiccarelliPublished in: Genome biology (2022)
Our study offers a comprehensive overview of our current understanding of the genetic events initiating clone expansion and cancer revealing significant gaps and biases that still need to be addressed. The compendium of cancer and non-cancer somatic drivers, their literature support, and properties are accessible in the Network of Cancer Genes and Healthy Drivers resource at http://www.network-cancer-genes.org/ .