Hypertension Severity as Quantified by Hypertension Daily Dose and Blood Pressure With Risk of Stroke in REGARDS.
Ying K LooKatherine S WilkinsonTyler HarknessGeorge HowardVirginia J HowardSuzanne E JuddNeil A ZakaiPaul MuntnerLillian MinSuzanne OparilTimothy B PlantePublished in: Journal of the American Heart Association (2024)
Among adults without prior stroke, systolic BP ≥140 mm Hg and HDD tertile ≥2 was associated with greater stroke risk. For adults with BP <140 mm Hg, stroke risk was similar despite cumulative dose of antihypertensive medications used. These findings support the practice of BP-lowering medications to mitigate stroke risk.