Immunogenicity and efficacy of VLA2001 vaccine against SARS-CoV-2 infection in male cynomolgus macaques.
Mathilde GalhautUrban LundbergRomain MarlinRobert SchleglStefan SeidelUrsula BartuschkaJürgen Heindl-WrussFrancis RelouzatSébastien LangloisNathalie BosquetJulie MorinMaxence Galpin-LebreauAnne-Sophie GallouëtWesley GrosThibaut NaninckQuentin PascalCatherine ChaponKarine MouchainGuillaume FichetJulien LemaitreMariangela CavarelliVanessa ContrerasNicolas LegrandAndreas MeinkeRoger Le GrandPublished in: Communications medicine (2024)
We demonstrate that the VLA2001 adjuvanted vaccine is immunogenic both in mouse and NHP models and prevent cynomolgus macaques from the viruses responsible of COVID-19.