The Effect of Berberine on Reproduction and Metabolism in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomized Control Trials.

Liangzhen XieDuojia ZhangHongli MaHui HeQing XiaWenjuan ShenHui ChangYingying DengQi WuJing CongChi Chiu Wang Xiao-Ke Wu

Published in: Evidence-based complementary and alternative medicine : eCAM (2019)

This review found no solid evidence that berberine could improve live birth or other clinical outcomes in women with PCOS. However, berberine appeared to be more efficacious for improving insulin resistance and dyslipidemia and decreasing androgen levels and LH/FSH ratio in women with PCOS when compared with metformin.

Keyphrases

polycystic ovary syndrome
insulin resistance
adipose tissue
metabolic syndrome
high fat diet
double blind
open label
skeletal muscle
type diabetes
phase iii
clinical trial
pregnancy outcomes
placebo controlled
phase ii
pregnant women
study protocol