Protein array-based companion diagnostics in precision medicine.

Thomas Bouet Guldbæk Poulsen Azra Karamehmedovic Christopher Aboo Malene Møller JørgensenXiaobo YuXiangdong FangJonathan Michael Blackburn Claus Henrik NielsenTue W KragstrupAllan Stensballe

Published in: Expert review of molecular diagnostics (2020)

Recent advances in the field of protein arrays have enabled high-density arrays permitting large biomarker discovery studies, which are beneficial for future CDx assays. The density of protein arrays range from a single protein to proteome-wide arrays, allowing the discovery of protein signatures that may correlate with drug response. Protein arrays will undoubtedly play a key role in future CDx assays.

Keyphrases

high density
protein protein
high throughput
small molecule
binding protein
emergency department
gene expression