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Proteomic analysis of extracellular vesicles from a Plasmodium falciparum Kenyan clinical isolate defines a core parasite secretome.

Abdirahman I AbdiLu YuDavid GouldingMartin K RonoPhilip BejonJyoti ChoudharyJulian C Rayner
Published in: Wellcome open research (2017)
P. falciparum extracellular vesicles contain virulence-associated parasite proteins. Therefore, analysis of PfEVs contents from a range of clinical isolates, and their functional validation may improve our understanding of the virulence mechanisms of the parasite, and potentially identify targets for interventions or diagnostics.
Keyphrases
  • plasmodium falciparum
  • escherichia coli
  • pseudomonas aeruginosa
  • staphylococcus aureus
  • antimicrobial resistance
  • biofilm formation
  • physical activity
  • cystic fibrosis