A Cross-sectional Study Reveals a Chronic Low-grade Inflammation in Achalasia.

Li-Yun MaZu-Qiang LiuWei-Feng ChenLu YaoYun-Shi ZhongYi-Qun ZhangLi-Li MaWen-Zhen QinJian-Wei HuMing-Yan CaiZhen ZhangSheng-Li LinHao HuPing Hong ZhouQuan-Lin Li

Published in: Journal of gastroenterology and hepatology (2022)

Patients with achalasia suffered from chronic low-grade inflammation with dysregulated immune cells and mediators associated with disease duration. CD8+ T cells might be the key pathogenic subpopulation of achalasia. Our results provide an important immune cell signature of the pathogenesis of achalasia.

Keyphrases

low grade
high grade
oxidative stress
physical activity