Insulin receptor substrate 2 gene Gly1057Asp polymorphism is a risk factor for nonalcoholic fatty liver disease.
Shadi NouriTouraj MahmoudiFarzaneh HojjatiZeinab Nourmohammadi NajafabadiRadmehr ShafieeShiva SayedsalehiAtefeh DehghanitaftiAbbas ArdalaniKiarash KohansalGholamreza RezamandAsadollah AsadiHossein NobakhtReza DabiriHamid FarahaniSeidamir Pasha TabaeianMohammad Reza ZaliPublished in: Laboratory medicine (2023)
Our findings revealed for the first time that the Gly1057Asp Asp/Asp genotype of the IRS2 gene is a marker of increased NAFLD susceptibility; however, studies in other populations are required to confirm the results.