Vascular Ehlers-Danlos Syndrome: A Comprehensive Natural History Study in a Dutch National Cohort of 142 Patients.
Serwet DemirdasLisa M van den BersselaarRosan LechnerJessica BosSuzanne I M AlstersMarieke J H BaarsAnnette F BaasÖzlem BaysalSaskia N van der CrabbenEelco DulferNoor A A GiesbertzApollonia T J M Helderman-van den EndenYvonne Hilhorst-HofsteeMarlies J E KempersFenne L KomdeurBart L LoeysDanielle Majoor-KrakauerCharlotte W OckeloenEline Overwatervan J Peter TintelenMarsha VoorendtVivian de WaardAlessandra MaugeriHennie T BrüggenwirthIngrid M B H van de LaarArjan C HouwelingPublished in: Circulation. Genomic and precision medicine (2024)
variant, and physical appearance highly suggestive of vEDS are risk factors for the occurrence and early age of onset of major events. This national multicenter cohort study of Dutch individuals with vEDS provides a valuable basis for improving guidelines for the diagnosing, follow-up, and treatment of individuals with vEDS.