Induction of the Epithelial-to-Mesenchymal Transition of Human Colorectal Cancer by Human TNF-β (Lymphotoxin) and its Reversal by Resveratrol.

Constanze BuhrmannMina YazdiBastian PopperAjaikumar B KunnumakkaraBharat B AggarwalMehdi Shakibaei

Published in: Nutrients (2019)

These results suggest that resveratrol down-regulates TNF-β/TNF-βR-induced EMT, at least in part via specific suppression of NF-κΒ and FAK in CRC cells.

Keyphrases

endothelial cells
rheumatoid arthritis
induced apoptosis
high glucose
induced pluripotent stem cells
signaling pathway
epithelial mesenchymal transition
oxidative stress
immune response
cell cycle arrest
lps induced
drug induced
cell death
nuclear factor
toll like receptor
cell migration