Combined Molnupiravir and Nirmatrelvir Treatment Improves the Inhibitory Effect on SARS-CoV-2 in Rhesus Macaques.

Kyle RosenkeMatt C LewisFriederike FeldmannEric BohrnsenBenjamin SchwarzAtsushi OkumuraW Forrest BohlerJulie CallisonCarl ShaiaCatharine M BosioJamie LovaglioGreg SaturdayMichael A JarvisHeinz Feldmann

Published in: bioRxiv : the preprint server for biology (2022)

The combination of molnupiravir and nirmatrelvir inhibits SARS-CoV-2 replication and shedding more effectively than individual treatments in the rhesus macaque model.

Keyphrases

sars cov
respiratory syndrome coronavirus
replacement therapy