The inhibitory effect of AMP-activated protein kinase (AMPK) on chemokine and prostaglandin production in human endometrial stromal cells.
Yasushi KawanoHatsumi SatoKaori GotoMasakazu NishidaKaei NasuPublished in: Reproductive biology and endocrinology : RB&E (2021)
The production of IL-8, MCP-1, PGE2 and PGF2α induced by IL-1β in ESCs were involved in the negative regulatory mechanisms of AMPK. The substances that activate AMPK may be promising agents for the treatment of pathological problems such as dysmenorrhea.