Population pharmacokinetics of daptomycin in critically ill patients receiving extracorporeal membrane oxygenation.
Li-Chen ZhangQiu-Yue LiYu-Qiu ZhangTi-Chao ShanYuan LiYi-Hui LiHui HanWei-Dong QinHai-Peng GuoWei ZhaoBo-Hao TangXiao-Mei ChenPublished in: The Journal of antimicrobial chemotherapy (2024)
This is the first PopPK model of daptomycin in ECMO patients. Optimal dosage regimens considering efficacy, safety, and pathogens were provided for critical patients based on pharmacokinetic-pharmacodynamic analysis.
Keyphrases
- extracorporeal membrane oxygenation
- end stage renal disease
- acute respiratory distress syndrome
- ejection fraction
- newly diagnosed
- prognostic factors
- peritoneal dialysis
- methicillin resistant staphylococcus aureus
- patient reported outcomes
- respiratory failure
- staphylococcus aureus
- multidrug resistant
- patient reported