Duration of cytopenias with concomitant venetoclax and azole antifungals in acute myeloid leukemia.
Caitlin R RauschCourtney D D DiNardoAbhishek MaitiNadya J JammalTapan Mahendra KadiaKayleigh R MarxGautam BorthakurJ Michael SavoyNaveen PemmarajuAdam J DiPippoNaval G DaverSerena M ChewKoiji SasakiGhayas C IssaNicholas James ShortKoichi TakahashiMaro N OhanianJing NingLianchun XiaoYesid AlvaradoDimitrios P KontoyiannisFarhad RavandiHagop M KantarjianMarina Y KonoplevaPublished in: Cancer (2021)
VEN plus an HMA resulted in neutropenia and thrombocytopenia, with the latter prolonged in patients receiving concomitant azoles. Concomitant posaconazole or voriconazole and VEN (100 mg) resulted in similar ANC and PLT recovery times, suggesting the safety of these dosage combinations during course 1.