IL-15 is a biomarker involved in the development of rapidly progressive interstitial lung disease complicated with polymyositis/dermatomyositis.
Toshimasa ShimizuTomohiro KogaK FurukawaY HoraiK FujikawaA OkadaM OkamotoYushiro EndoS TsujiA TakataniM UmedaShoichi FukuiR SumiyoshiS-Y KawashiriN IwamotoT IgawaK IchinoseM TamaiN SakamotoHideki NakamuraT OriguchiH MukaeM KuwanaA KawakamiPublished in: Journal of internal medicine (2020)
This study identified a combination of biomarkers predicting PM/DM-RPILD progression, and IL-15 is an important cytokine for predicting RPILD development and reflecting ILD severity.