Noninvasive quantification of fibrosis in skeletal and cardiac muscle in mdx mice using EP3533 enhanced magnetic resonance imaging.

Alexander Peter MurphyElizabeth GreallyDara O'HogainAndrew BlamirePeter CaravanVolker Straub

Published in: Magnetic resonance in medicine (2018)

This study provides evidence for the suitability of EP3533 in the quantification of muscular fibrosis in mdx mice and demonstrated that EP3533-derived measurements correlated strongly to ex vivo fibrosis measurement.

Keyphrases

magnetic resonance imaging
duchenne muscular dystrophy
high fat diet induced
skeletal muscle
liver fibrosis
computed tomography
left ventricular
heart failure
type diabetes
magnetic resonance
insulin resistance