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SARS-CoV-2 N Protein Triggers Acute Lung Injury via Modulating Macrophage Activation and Infiltration in in vitro and in vivo.

Dengming LaiKun ZhuSisi LiYi XiaoQi XuYi-Sheng SunPingping YaoDaqing MaQiang Shu
Published in: Journal of inflammation research (2023)
SARS-CoV-2 and its N protein but not S protein induced acute lung injury and systemic inflammation, which was closely related to macrophage activation, infiltration and release cytokines.
Keyphrases
  • sars cov
  • lipopolysaccharide induced
  • lps induced
  • protein protein
  • respiratory syndrome coronavirus
  • binding protein
  • signaling pathway
  • inflammatory response
  • endothelial cells
  • drug induced
  • high glucose
  • small molecule