RNA therapeutics for mood disorders: current evidence toward clinical trials.

Marguerite Le MaroisEleni TzavaraEl Chérif Ibrahim Olivier Blin Raoul Belzeaux

Published in: Expert opinion on investigational drugs (2021)

Several promising RNA therapeutics have been tested in pre-clinical studies for MDD, whereas no molecule has been developed for BD. There are several issues to address before reaching clinical development and new challenges include stratifying patient population and predicting therapeutic response.

Keyphrases

clinical trial
small molecule
bipolar disorder
case report
nucleic acid
phase ii
physical activity
depressive symptoms