Effect of radiation therapy on cerebral cortical thickness in glioma patients: Treatment-induced thinning of the healthy cortex.
Steven H J NagtegaalSzabolcs DavidTom Jan SnijdersMarielle E P PhilippensAlexander LeemansJoost J C VerhoeffPublished in: Neuro-oncology advances (2020)
We have identified three areas susceptible to dose-dependent cortical thinning after radiation therapy. Should future prospective studies conclude that irradiation of these areas lead to cognitive decline, they need to be spared in order to prevent this debilitating consequence of treatment.
Keyphrases
- radiation therapy
- cognitive decline
- end stage renal disease
- mild cognitive impairment
- chronic kidney disease
- newly diagnosed
- ejection fraction
- peritoneal dialysis
- subarachnoid hemorrhage
- neuropathic pain
- functional connectivity
- spinal cord injury
- blood brain barrier
- endothelial cells
- drug induced
- replacement therapy