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Automated scoring of dicentric chromosomes differentiates increased radiation sensitivity of young children after low dose CT exposure in vitro.

Ursula OestreicherDavid EndesfelderMaria GomolkaAusrele KesminienePeter LangCarita LindholmUte RößlerDaniel SamagaUlrike M Kulka
Published in: International journal of radiation biology (2018)
The results very clearly demonstrate that the automated dicentric scoring method is capable of discerning radiation induced biomarkers in the low dose range (<100 mGy) and thus may open possibilities for large-scale molecular epidemiology studies in radiation protection.
Keyphrases
  • radiation induced
  • low dose
  • radiation therapy
  • deep learning
  • machine learning
  • high dose
  • high throughput
  • computed tomography
  • minimally invasive
  • contrast enhanced
  • dual energy
  • case control