Review article: the genetics of the human leucocyte antigen region in inflammatory bowel disease.

James John AshtonKaty LathamRobert Mark Beattie Sarah Ennis

Published in: Alimentary pharmacology & therapeutics (2019)

The HLA complex is associated with multiple risk/protective alleles for IBD. Future research utilising long-read technology, ascertainment of zygosity and integration in disease modelling will improve the functional understanding and clinical translation of genetic findings.

Keyphrases

endothelial cells
induced pluripotent stem cells
current status
genome wide
single molecule
copy number
ulcerative colitis