Phenotypes of Chronic Covert Brain Infarction in Patients With First-Ever Ischemic Stroke: A Cohort Study.
Jan VynckierJohannes KaesmacherJoanna Marguerite WardlawLaurent RotenMorin BeyelerNebiyat Filate BelachewLorenz GrunderDavid Julian SeiffgeSimon JungJan GrallaTomas DobrockyMirjam Rachel HeldnerUlrike PrangeMartina Béatrice GoeldlinMarcel ArnoldUrs FischerThomas Raphael MeinelPublished in: Stroke (2021)
CBIs were present in more than a third of patients with first AIS. Their location and phenotypes as determined by MRI were different from previous studies using computed tomography imaging. Among patients suffering from AIS, those with additional CBI represent a vascular high-risk subgroup and the association of different phenotypes of CBIs with differing risk factor profiles potentially points toward discriminative AIS etiologies.