COVID-19 clinical outcomes and DMT of MS patients and population-based controls.
Elisa LonginettiHannah BowerKyla A McKaySimon EnglundJoachim BurmanKatharina FinkAnna Fogdell-HahnMartin GunnarssonJan HillertAnnette M Langer-GouldJan LyckePetra NilssonJonatan SalzerAnders SvenningssonJohan MellergårdTomas OlssonFredrik PiehlThomas FrisellPublished in: Annals of clinical and translational neurology (2022)
Risks of severe COVID-19-related outcomes were increased among multiple sclerosis patients as a whole compared to population controls, but risk increases were also seen for non-COVID-19 hospitalization, intensive care admission, and mortality, and did not significantly differ during the pandemic compared to pre-pandemic years. The risk conveyed by disease-modifying therapies was smaller than previously assumed, likely as a consequence of the possibility to better control for confounders.