CCNE1 and survival of patients with tubo-ovarian high-grade serous carcinoma: An Ovarian Tumor Tissue Analysis consortium study.
Eun-Young KangAshley WeirNicola S MeagherKyo FarringtonGregg S NelsonPrafull GhatageCheng-Han LeeMarjorie J RigganAdelyn BolithonGordana PopovicBetty LeungKatrina TangNeil LambieJoshua MillsteinJennifer AlsopMichael S AnglesioBeyhan AtasevenEllen BarlowMatthias W BeckmannJessica BergerChristiani BisinottoHans BösmüllerJessica BorosAlison H BrandAngela Brooks-WilsonSara Y BruckerMichael E CarneyYovanni CasablancaAlicia Cazorla-JiménezPaul A CohenThomas P ConradsLinda S CookPenny CoulsonMadeleine Courtney-BrooksDaniel W CramerPhilip CroweJulie M CunninghamCezary CybulskiKathleen M DarcyMona A El-BahrawyEsther ElishaevRamona ErberRhonda FarrellSian FeredayAnna FischerMaría J GarcíaSimon A GaytherAleksandra Gentry-MaharajC Blake Gilksnull nullMarcel GrubePaul R HarnettShariska Petersen HarringtonPhilipp HarterArndt HartmannJonathan L HechtSebastian HeikausAlexander HeinFlorian HeitzJoy HendleyBrenda Y HernandezSusanna Hernando PoloSabine HeubleinAkira HirasawaEstrid HøgdallClaus K HøgdallHugo M HorlingsDavid G HuntsmanTomasz HuzarskiAndrea JewellMercedes Jimenez-LinanMichael E JonesScott H KaufmannCatherine J KennedyDineo KhabeleFelix K F KommossRoy F P M KruitwagenDiether LambrechtsNhu D LeMarcin LenerJenny LesterYee LeungAnna LinderLiselore LoverixJan LubińskiRashna MadanG Larry MaxwellFrancesmary ModugnoSusan L NeuhausenAlexander OlawaiyeSiel OlbrechtSandra OrsulicJosé PalaciosCeleste Leigh PearceMalcolm C PikeCarmel M QuinnGanendra Raj MohanCristina Rodríguez-AntonaMatthias RuebnerAndy RyanStuart G SalfingerNaoko SasamotoJoellen M SchildkrautMinouk J SchoemakerMitul ShahRaghwa SharmaYurii B ShvetsovNaveena SinghGabe S SonkeLinda SteeleColin J R StewartKarin SundfeldtAnthony J SwerdlowAline TalhoukAdeline TanSarah E TaylorKathryn L TerryAleksandra TołoczkoNadia TraficanteKoen K Van de VijverMaaike A van der AaToon Van GorpEls Van NieuwenhuysenLilian van-WagensveldIgnace VergoteRobert A VierkantChen WangLynne R WilkensStacey J WinhamAnna H WuJavier BenitezAndrew BerchuckFrancisco J Candido Dos ReisAnna DeFazioPeter A FaschingEllen L GoodeMarc T GoodmanJacek GronwaldBeth Y KarlanStefan KommossUsha MenonHans-Peter SinnAnnette StaeblerJames D BrentonDavid D BowtellPaul D P PharoahSusan J RamusMartin KoebelPublished in: Cancer (2022)
This study provides large-scale validation that CCNE1 high-level amplification is associated with shorter survival, supporting its utility as a prognostic biomarker in HGSC.
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