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Neferine alleviates ovariectomy-induced osteoporosis by enhancing osteogenic differentiation of bone marrow mesenchymal stem cells via regulation of the p38MAPK pathway.

Jianwei LiangDandan BaoZhan YeBinhao CaoZhenyu LuJianjun Chen
Published in: Connective tissue research (2024)
Neferine can boost the osteoblastic differentiation of BMSCs and alleviate OVX-induced osteoporosis in rats by activating the p38MAPK signaling pathway.
Keyphrases
  • signaling pathway
  • high glucose
  • postmenopausal women
  • diabetic rats
  • bone mineral density
  • epithelial mesenchymal transition
  • oxidative stress
  • mouse model
  • vascular smooth muscle cells
  • body composition
  • angiotensin ii