Deferring gonadectomy in patients with turner syndrome with a genetic Y component is not a safe practice.
Sameer MittalJohn WeaverAznive AghababianRebecca EdwinsKarl GodlewskiKatherine FischerSharmayne SiuDenise GruccioJason Van BataviaArun SrinivasanChristopher LongVaneeta BambaVandana BatraTricia BhattiThomas KolonPublished in: Journal of pediatric urology (2023)
TSY patients cannot be safely observed for tumor formation based on clinical factors such as imaging or age. Gonadectomy is safe with a low complication rate and without tumor recurrence during three-year follow-up. We continue to recommend bilateral gonadectomy in this patient population at the time of diagnosis.