Login / Signup

Ag-Catalyzed ring-opening of tertiary cycloalkanols for C-H functionalization of cyclic aldimines.

Jingjing WangXue LiuZiyan WuFeng LiMing-Liang ZhangYiman MiJunhao WeiYao ZhouLan-Tao Liu
Published in: Chemical communications (Cambridge, England) (2021)
We firstly describe a silver-catalyzed direct C-H functionalization of cyclic aldimines with cyclopropanols and cyclobutanols via a radical-mediated C-C bond cleavage strategy. The desired products were generated in decent yields with wide substrate scope under mild reaction conditions. In addition, a gram-scale reaction and synthetic transformation of the product were performed.
Keyphrases
  • room temperature
  • gold nanoparticles
  • electron transfer
  • gram negative
  • quantum dots
  • dna binding
  • ionic liquid
  • multidrug resistant
  • transcription factor
  • transition metal