Immunogenicity, efficacy, and safety of SARS-CoV-2 vaccine dose fractionation: a systematic review and meta-analysis.
Bingyi YangXiaotong HuangHuizhi GaoNancy H LeungTim K TsangBenjamin J CowlingPublished in: BMC medicine (2022)
Dose fractionation of mRNA and protein subunit vaccines may be safe and effective, which would also vary depending on the characteristics of emerging variants and updated vaccine formulations.