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Amantadine and/or transcranial magnetic stimulation for fatigue associated with multiple sclerosis (FETEM): study protocol for a phase 3 randomised, double-blind, cross-over, controlled clinical trial.

Jordi A Matias-GuiuJavier González-RosaMiguel Ángel HernándezMaria Luisa Martínez-GinésAntonio PortolésNatalia Pérez-MacíasJulián Benito-LeónIván PadrónJulio PrietoJorge Matias-Guiu
Published in: BMJ open (2024)
EudraCT 2021-004868-95; NCT05809414.
Keyphrases
  • transcranial magnetic stimulation
  • double blind
  • multiple sclerosis
  • clinical trial
  • high frequency
  • placebo controlled
  • phase ii
  • phase iii
  • open label
  • study protocol
  • sleep quality
  • white matter
  • depressive symptoms