Radiosynthesis and Preliminary Biological Evaluation of 18F-Fluoropropionyl-Chlorotoxin as a Potential PET Tracer for Glioma Imaging.

Jing ZhaoYu-Liang WangXin-Bei LiSi-Yuan GaoShao-Yu LiuYu-Kun SongJing-Yan WangYing XiongHui MaLi JiangZhi-Yun YangGang-Hua Tang Jian-Ping Chu

Published in: Contrast media & molecular imaging (2018)

Compared with [18F]-FDG, [18F]-FP-chlorotoxin has a low and stable uptake in normal brain parenchyma. [18F]-FP-Chlorotoxin seems to be a potential PET tracer with a good performance in diagnosis of the glioma.

Keyphrases

pet imaging
positron emission tomography
computed tomography
pet ct
high resolution
human health
white matter
cerebral ischemia
resting state
fluorescence imaging