A proof-of-concept study on the use of a fluorescein-based 18 F-tracer for pretargeted PET.
Hugo HelbertEmily M PloegDouwe F SamploniusSimon N BlokInes F AntunesVerena I BöhmerGert LuurtsemaRudi A J O DierckxBen L FeringaPhilip H ElsingaWiktor SzymanskiWijnand HelfrichPublished in: EJNMMI radiopharmacy and chemistry (2022)
F-tracer, is presented. It is shown to selectively target EpCAM-expressing cells in vitro and its further evaluation with different bispecific antibodies demonstrates the versatility of the approach.