FAR Ratio as Prognostic Biomarker in AMI.
Ali MuhtarogluRecayi ÇapoğluFurkan Ali UygurAhmet Tarık HarmantepeZülfü BayhanEmre GönüllüPublished in: SN comprehensive clinical medicine (2023)
Acute mesenteric ischemia (AMI) is a vascular emergency resulting from decreased blood flow caused by the occlusion of the mesenteric vessels, hypoperfusion, or vasospasm. This study aimed to investigate the prognostic value of the fibrinogen-to-albumin (FAR) ratio in patients with acute mesenteric ischemia. A total of 91 patients were enrolled in the study. Patients' demographics such as age and gender, pre- and postoperative hemoglobin, CRP, white blood cell (WBC), neutrophils, preoperative lymphocyte, alanine transaminase (ALT), aspartate transaminase (AST), thrombocytes, and postoperative D-dimer values were recorded. In addition, pre- and postoperative fibrinogen and albumin levels were recorded, and FAR was calculated. Patients were divided into two groups, survivors and non-survivors. The mean pre- and postoperative fibrinogen levels were statistically significantly higher in the non-survivor group than in the survivor group ( p < 0.001). The mean pre- and postoperative albumin levels were significantly lower in the non-survivors than in the survivors ( p = 0.059, p < 0.001; respectively). The mean pre- and postoperative FAR ratios were considerably higher in the non-survivor than in the survivor groups ( p < 0.001). The change between pre- and postoperative fibrinogen, albumin, and FAR values was statistically significant between the non-survivors and the survivors (for all, p < 0.05). The preoperative and postoperative fibrinogen levels were significantly lower, and albumin levels were significantly higher in the survivor compared to the non-survivor patients with AMI. Furthermore, the preoperative and postoperative FAR ratio was significantly higher in the non-survivors. The FAR ratio may be a valuable prognostic biomarker for patients with AMI.
Keyphrases
- patients undergoing
- end stage renal disease
- young adults
- chronic kidney disease
- ejection fraction
- newly diagnosed
- acute myocardial infarction
- blood flow
- peritoneal dialysis
- emergency department
- stem cells
- prognostic factors
- heart failure
- acute coronary syndrome
- hepatitis b virus
- mesenchymal stem cells
- coronary artery disease
- left ventricular
- cell therapy
- brain injury
- mental health
- atrial fibrillation
- percutaneous coronary intervention