Does prior administration of rtPA influence acute ischemic stroke clot composition? Findings from the analysis of clots retrieved with mechanical thrombectomy from the RESTORE registry.
Rosanna RossiSara MolinaOana Madalina MereutaAndrew DouglasSeán FitzgeraldCiara TierneyAbhay PanditPaul BrennanSarah PowerAlan O'HareMichael GilvarryRay McCarthyGeorgios MagoufisGeorgios TsivgoulisAndrás NagyÁgnes VadászKatarina JoodPetra RedforsAnnika NordanstigErik CederDennis DunkerJeanette CarlqvistKlearchos PsychogiosIstván SzikoraTurgut TatlisumakAlexandros RentzosJohn ThorntonKaren M DoylePublished in: Journal of neurology (2021)
Our results suggest that previous IVT administration significantly reduces thrombus size, proportionally releasing all the main histological components.
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