Single cell RNA-Seq reveals pre-cDCs fate determined by transcription factor combinatorial dose.
Wenji MaJaeyop LeeDaniel BackenrothYu Jerry ZhouErin BushPeter SimsKang LiuYufeng ShenPublished in: BMC molecular and cell biology (2019)
In this study, we demonstrate that single cell transcriptome profiling can reveal pre-cDCs differentiation map, and our results suggest the concept that combinatorial dose of transcription factors determines cell differentiation fate.