Single cell RNA-Seq reveals pre-cDCs fate determined by transcription factor combinatorial dose.

Wenji MaJaeyop LeeDaniel BackenrothYu Jerry ZhouErin BushPeter SimsKang LiuYufeng Shen

Published in: BMC molecular and cell biology (2019)

In this study, we demonstrate that single cell transcriptome profiling can reveal pre-cDCs differentiation map, and our results suggest the concept that combinatorial dose of transcription factors determines cell differentiation fate.

Keyphrases

single cell
rna seq
transcription factor
high throughput
dna binding
gene expression
high density