The Alzheimer's comorbidity phenome: mining from a large patient database and phenome-driven genetics prediction.

Published in: JAMIA open (2018)

We innovatively leveraged FAERS, a comprehensive data resource for FDA postmarket drug safety surveillance, for large-scale AD comorbidity mining. This exploratory study demonstrated the potential of disease-comorbidities mining from FAERS in AD genetics discovery.

Keyphrases

public health
small molecule
adverse drug
case report
electronic health record
high throughput
cognitive decline
big data
climate change
human health
single cell
drug administration