Myoprotective effects of bFGF on skeletal muscle injury in pressure-related deep tissue injury in rats.

Hongxue ShiHaohuang XieYan ZhaoCai LinFeifei CuiYingying PanXiaohui WangJingjing ZhuPingtao CaiHongyu ZhangXiaobing FuZhou-Guang WangLiping Jiang

Published in: Burns & trauma (2016)

Our findings show that bFGF accelerated injured skeletal muscle regeneration through activation of the PI3K/Akt/mTOR signaling pathway and suggest that administration of bFGF is a potential therapeutic strategy for the treatment of skeletal muscle injury in PUs.

Keyphrases

skeletal muscle
insulin resistance
signaling pathway
stem cells
pi k akt
epithelial mesenchymal transition
oxidative stress
metabolic syndrome
combination therapy
drug induced