Randomized Trial of Metformin, Ivermectin, and Fluvoxamine for Covid-19.
Carolyn T BramanteJared D HulingChristopher J TignanelliJohn B BuseDavid M LiebovitzJacinda M NicklasKenneth CohenMichael A PuskarichHrishikesh K BelaniJennifer L ProperLianne K SiegelNichole R KlattDavid J OddeDarlette G LukeBlake AndersonAmy B KargerNicholas E IngrahamKatrina M HartmanVia RaoAubrey A HagenBarkha PatelSarah L FennoNandini AvulaNeha V ReddySpencer M EricksonSarah LindbergRegina FrictonSamuel LeeAdnin ZamanHanna G SaveraidWalker J TordsenMatthew F PullenMichelle BirosNancy E SherwoodJennifer L ThompsonDavid R BoulwareThomas A Murraynull nullPublished in: The New England journal of medicine (2022)
None of the three medications that were evaluated prevented the occurrence of hypoxemia, an emergency department visit, hospitalization, or death associated with Covid-19. (Funded by the Parsemus Foundation and others; COVID-OUT ClinicalTrials.gov number, NCT04510194.).