The Impact of Risk-Adjusted Heparin Regimens on the Outcome of Patients with COVID-19 Infection. A Prospective Cohort Study.
Pierpaolo Di MiccoAntonella TufanoGiuseppe CardilloEgidio ImbalzanoMaria AmitranoCorrado LodigianiAnnamaria BellizziGiuseppe CamporeseAntonella CavalliCarmela De StefanoVincenzo RussoAntonio VozaAlessandro PerrellaPaolo PrandoniPublished in: Viruses (2021)
Despite the use of risk-adjusted doses of enoxaparin, the rate of VTE events was consistent with that reported in contemporary studies where fixed-dose low-molecular-weight heparin was used. The unexpectedly high risk of bleeding complications should induce caution in administering enoxaparin in doses higher than the conventional low ones.