α-Spinasterol: a COX inhibitor and a transient receptor potential vanilloid 1 antagonist presents an antinociceptive effect in clinically relevant models of pain in mice.
Indiara BruscoCamila CamponogaraFabiano Barbosa CarvalhoMaria Rosa Chitolina SchetingerMauro Schneider OliveiraGabriela TrevisanJuliano FerreiraSara Marchesan OliveiraPublished in: British journal of pharmacology (2017)
α-Spinasterol is an effective and safe COX inhibitor with antinociceptive effects in postoperative and neuropathic pain models. Therefore, it is an interesting prototype for the development of novel analgesic drugs.