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Discontinuing cotrimoxazole preventive therapy in HIV-infected adults who are stable on antiretroviral treatment in Uganda (COSTOP): A randomised placebo controlled trial.

Zacchaeus AnywaineJonathan LevinRonnie KasiryeJoseph Kayiira LutaakomeAndrew AbaasaAndrew NunnHeiner GrosskurthPaula Munderinull null
Published in: PloS one (2018)
In ART stable patients with CD4 counts ≥250 cells/μL, continued CPT significantly reduces risk of severe bacterial infections and protects against malaria, while discontinuing CPT reduces haematological adverse events.
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