Six-Digit CPK and Mildly Affected Renal Function in McArdle Disease.
George SpyropoulosPanagiotis KratimenosAndrew D McinnesRichard J DeGrooteIoannis KoutroulisPublished in: Case reports in pediatrics (2014)
A previously healthy, white 12-year-old girl presented with diffuse body aches and poor perfusion. She developed severe respiratory failure and marked rhabdomyolysis and was mechanically ventilated. Although her CPK peaked at 500,000 IU/L, her renal function was mildly affected and her creatinine did not exceed the 0.8 mg/dL. The rhabdomyolysis was gradually resolved following aggressive fluid hydration. The patient did not require dialysis and made a complete recovery. Genetic studies revealed the diagnosis of McArdle disease.
Keyphrases
- respiratory failure
- acute kidney injury
- extracorporeal membrane oxygenation
- mechanical ventilation
- intensive care unit
- acute respiratory distress syndrome
- chronic kidney disease
- early onset
- end stage renal disease
- low grade
- genome wide
- uric acid
- computed tomography
- magnetic resonance
- dna methylation
- contrast enhanced