The immunome of soy bean allergy: Comprehensive identification and characterization of epitopes.
Karolin KernHeide HavenithNicolas DelaroquePaul RautenbergerJörg LehmannMarkus FischerHolger SpiegelStefan SchillbergEva Ehrentreich-FoersterStefanie AurichRegina TreudlerMichael SzardeningsPublished in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2018)
For individuals with clinical symptoms, epitope resolved analyses reveal a high prevalence of IgE binding to a few soy bean specific epitopes. Evaluation of individual immune profiles of patients with soy bean sensitization allows the identification of peptides that do facilitate studying individual IgE/IgG epitope binding patterns. This enables discrimination of sensitization from disease, such assay test has the potential to replace SPT assays.