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High-Dosage NMN Promotes Ferroptosis to Suppress Lung Adenocarcinoma Growth through the NAM-Mediated SIRT1-AMPK-ACC Pathway.
Mingjiong Zhang
Jiahua Cui
Haoyan Chen
Yu Wang
Xingwang Kuai
Sibo Sun
Qi Tang
Feng Zong
Qiaoyu Chen
Jianqing Wu
Shuangshuang Wu
Published in:
Cancers (2023)
This study highlights the tumor influence of NMN at high doses in the manipulation of cancer cell metabolism, providing a new perspective on clinical therapy in patients with lung adenocarcinoma.
Keyphrases
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oxidative stress
skeletal muscle
ischemia reperfusion injury
stem cells
smoking cessation
cell therapy