Aortic stenosis in homozygous familial hypercholesterolaemia: a paradigm shift over a century.
Alexandre M BélangerLeo E AkioyamenIsabelle RuelLindsay HalesJacques GenestPublished in: European heart journal (2022)
These data suggest that SVAS and VAS are frequent in HoFH and that the phenotype has shifted towards calcific VAS as statins and lipoprotein apheresis improve survival in these patients.
Keyphrases
- ejection fraction
- aortic stenosis
- end stage renal disease
- transcatheter aortic valve replacement
- aortic valve replacement
- transcatheter aortic valve implantation
- newly diagnosed
- chronic kidney disease
- aortic valve
- left ventricular
- cardiovascular disease
- peritoneal dialysis
- heart failure
- prognostic factors
- electronic health record
- early onset
- coronary artery disease
- patient reported